Redox Modification of the Iron-Sulfur Glutaredoxin GRXS17 Activates Holdase Activity and Protects Plants from Heat Stress.
Identifieur interne : 000026 ( Main/Exploration ); précédent : 000025; suivant : 000027Redox Modification of the Iron-Sulfur Glutaredoxin GRXS17 Activates Holdase Activity and Protects Plants from Heat Stress.
Auteurs : Laura Martins [France] ; Johannes Knuesting [Allemagne] ; Laetitia Bariat [France] ; Avilien Dard [France] ; Sven A. Freibert [Allemagne] ; Christophe H. Marchand [France] ; David Young [Belgique] ; Nguyen Ho Thuy Dung [Belgique] ; Wilhelm Voth [États-Unis] ; Anne Debures [France] ; Julio Saez-Vasquez [France] ; Stéphane D. Lemaire [France] ; Roland Lill [Allemagne] ; Joris Messens [Belgique] ; Renate Scheibe [Allemagne] ; Jean-Philippe Reichheld [France] ; Christophe Riondet [France]Source :
- Plant physiology [ 1532-2548 ] ; 2020.
Abstract
Heat stress induces misfolding and aggregation of proteins unless they are guarded by chaperone systems. Here, we examined the function of the glutaredoxin GRXS17, a member of thiol reductase families in the model plant Arabidopsis (Arabidopsis thaliana). GRXS17 is a nucleocytosolic monothiol glutaredoxin consisting of an N-terminal thioredoxin domain and three CGFS active-site motif-containing GRX domains that coordinate three iron-sulfur (Fe-S) clusters in a glutathione-dependent manner. As an Fe-S cluster-charged holoenzyme, GRXS17 is likely involved in the maturation of cytosolic and nuclear Fe-S proteins. In addition to its role in cluster biogenesis, GRXS17 presented both foldase and redox-dependent holdase activities. Oxidative stress in combination with heat stress induced loss of its Fe-S clusters followed by subsequent formation of disulfide bonds between conserved active-site cysteines in the corresponding thioredoxin domains. This oxidation led to a shift of GRXS17 to a high-molecular-weight complex and thus activated its holdase activity in vitro. Moreover, GRXS17 was specifically involved in plant tolerance to moderate high temperature and protected root meristematic cells from heat-induced cell death. Finally, GRXS17 interacted with a different set of proteins upon heat stress, possibly protecting them from heat injuries. Therefore, we propose that the Fe-S cluster enzyme GRXS17 is an essential guard that protects proteins against moderate heat stress, likely through a redox-dependent chaperone activity. We reveal the mechanism of an Fe-S cluster-dependent activity shift that converts the holoenzyme GRXS17 into a holdase, thereby preventing damage caused by heat stress.
DOI: 10.1104/pp.20.00906
PubMed: 32826321
PubMed Central: PMC7536686
Affiliations:
- Allemagne, Belgique, France, États-Unis
- Basse-Saxe, District de Giessen, Hesse (Land), Languedoc-Roussillon, Michigan, Occitanie (région administrative), Région de Bruxelles-Capitale, Île-de-France
- Bruxelles, Marbourg, Osnabrück, Paris, Perpignan
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Quantitative Biology, Unité Mixte de Recherche 7238, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lill, Roland" sort="Lill, Roland" uniqKey="Lill R" first="Roland" last="Lill">Roland Lill</name><affiliation wicri:level="3"><nlm:affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Messens, Joris" sort="Messens, Joris" uniqKey="Messens J" first="Joris" last="Messens">Joris Messens</name><affiliation wicri:level="1"><nlm:affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>VIB-VUB Center for Structural Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Brussels Center for Redox Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Scheibe, Renate" sort="Scheibe, Renate" uniqKey="Scheibe R" first="Renate" last="Scheibe">Renate Scheibe</name><affiliation wicri:level="3"><nlm:affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Reichheld, Jean Philippe" sort="Reichheld, Jean Philippe" uniqKey="Reichheld J" first="Jean-Philippe" last="Reichheld">Jean-Philippe Reichheld</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France jpr@univ-perp.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Riondet, Christophe" sort="Riondet, Christophe" uniqKey="Riondet C" first="Christophe" last="Riondet">Christophe Riondet</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32826321</idno><idno type="pmid">32826321</idno><idno type="doi">10.1104/pp.20.00906</idno><idno type="pmc">PMC7536686</idno><idno type="wicri:Area/Main/Corpus">000032</idno><idno type="wicri:explorRef" 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(région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Knuesting, Johannes" sort="Knuesting, Johannes" uniqKey="Knuesting J" first="Johannes" last="Knuesting">Johannes Knuesting</name><affiliation wicri:level="3"><nlm:affiliation>Department of Plant Physiology, FB5, University of Osnabrück, D-49069 Osnabrueck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Plant Physiology, FB5, University of Osnabrück, D-49069 Osnabrueck</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Osnabrück</settlement></placeName></affiliation></author><author><name sortKey="Bariat, Laetitia" sort="Bariat, Laetitia" uniqKey="Bariat L" first="Laetitia" last="Bariat">Laetitia Bariat</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Dard, Avilien" sort="Dard, Avilien" uniqKey="Dard A" first="Avilien" last="Dard">Avilien Dard</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Freibert, Sven A" sort="Freibert, Sven A" uniqKey="Freibert S" first="Sven A" last="Freibert">Sven A. Freibert</name><affiliation wicri:level="3"><nlm:affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Marchand, Christophe H" sort="Marchand, Christophe H" uniqKey="Marchand C" first="Christophe H" last="Marchand">Christophe H. Marchand</name><affiliation wicri:level="3"><nlm:affiliation>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Young, David" sort="Young, David" uniqKey="Young D" first="David" last="Young">David Young</name><affiliation wicri:level="1"><nlm:affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>VIB-VUB Center for Structural Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Brussels Center for Redox Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Dung, Nguyen Ho Thuy" sort="Dung, Nguyen Ho Thuy" uniqKey="Dung N" first="Nguyen Ho Thuy" last="Dung">Nguyen Ho Thuy Dung</name><affiliation wicri:level="1"><nlm:affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>VIB-VUB Center for Structural Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Brussels Center for Redox Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Voth, Wilhelm" sort="Voth, Wilhelm" uniqKey="Voth W" first="Wilhelm" last="Voth">Wilhelm Voth</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor</wicri:cityArea></affiliation></author><author><name sortKey="Debures, Anne" sort="Debures, Anne" uniqKey="Debures A" first="Anne" last="Debures">Anne Debures</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Saez Vasquez, Julio" sort="Saez Vasquez, Julio" uniqKey="Saez Vasquez J" first="Julio" last="Saez-Vasquez">Julio Saez-Vasquez</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Lemaire, Stephane D" sort="Lemaire, Stephane D" uniqKey="Lemaire S" first="Stéphane D" last="Lemaire">Stéphane D. Lemaire</name><affiliation wicri:level="3"><nlm:affiliation>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Unité Mixte de Recherche 7238, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Unité Mixte de Recherche 7238, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lill, Roland" sort="Lill, Roland" uniqKey="Lill R" first="Roland" last="Lill">Roland Lill</name><affiliation wicri:level="3"><nlm:affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Messens, Joris" sort="Messens, Joris" uniqKey="Messens J" first="Joris" last="Messens">Joris Messens</name><affiliation wicri:level="1"><nlm:affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>VIB-VUB Center for Structural Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Brussels Center for Redox Biology, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Scheibe, Renate" sort="Scheibe, Renate" uniqKey="Scheibe R" first="Renate" last="Scheibe">Renate Scheibe</name><affiliation wicri:level="3"><nlm:affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Reichheld, Jean Philippe" sort="Reichheld, Jean Philippe" uniqKey="Reichheld J" first="Jean-Philippe" last="Reichheld">Jean-Philippe Reichheld</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France jpr@univ-perp.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author><author><name sortKey="Riondet, Christophe" sort="Riondet, Christophe" uniqKey="Riondet C" first="Christophe" last="Riondet">Christophe Riondet</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Languedoc-Roussillon</region><settlement type="city">Perpignan</settlement></placeName></affiliation></author></analytic><series><title level="j">Plant physiology</title><idno type="eISSN">1532-2548</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Heat stress induces misfolding and aggregation of proteins unless they are guarded by chaperone systems. Here, we examined the function of the glutaredoxin GRXS17, a member of thiol reductase families in the model plant Arabidopsis (<i>Arabidopsis thaliana</i>). GRXS17 is a nucleocytosolic monothiol glutaredoxin consisting of an N-terminal thioredoxin domain and three CGFS active-site motif-containing GRX domains that coordinate three iron-sulfur (Fe-S) clusters in a glutathione-dependent manner. As an Fe-S cluster-charged holoenzyme, GRXS17 is likely involved in the maturation of cytosolic and nuclear Fe-S proteins. In addition to its role in cluster biogenesis, GRXS17 presented both foldase and redox-dependent holdase activities. Oxidative stress in combination with heat stress induced loss of its Fe-S clusters followed by subsequent formation of disulfide bonds between conserved active-site cysteines in the corresponding thioredoxin domains. This oxidation led to a shift of GRXS17 to a high-molecular-weight complex and thus activated its holdase activity in vitro. Moreover, GRXS17 was specifically involved in plant tolerance to moderate high temperature and protected root meristematic cells from heat-induced cell death. Finally, GRXS17 interacted with a different set of proteins upon heat stress, possibly protecting them from heat injuries. Therefore, we propose that the Fe-S cluster enzyme GRXS17 is an essential guard that protects proteins against moderate heat stress, likely through a redox-dependent chaperone activity. We reveal the mechanism of an Fe-S cluster-dependent activity shift that converts the holoenzyme GRXS17 into a holdase, thereby preventing damage caused by heat stress.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">32826321</PMID><DateRevised><Year>2020</Year><Month>10</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2548</ISSN><JournalIssue CitedMedium="Internet"><Volume>184</Volume><Issue>2</Issue><PubDate><Year>2020</Year><Month>10</Month></PubDate></JournalIssue><Title>Plant physiology</Title><ISOAbbreviation>Plant Physiol</ISOAbbreviation></Journal><ArticleTitle>Redox Modification of the Iron-Sulfur Glutaredoxin GRXS17 Activates Holdase Activity and Protects Plants from Heat Stress.</ArticleTitle><Pagination><MedlinePgn>676-692</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1104/pp.20.00906</ELocationID><Abstract><AbstractText>Heat stress induces misfolding and aggregation of proteins unless they are guarded by chaperone systems. Here, we examined the function of the glutaredoxin GRXS17, a member of thiol reductase families in the model plant Arabidopsis (<i>Arabidopsis thaliana</i>). GRXS17 is a nucleocytosolic monothiol glutaredoxin consisting of an N-terminal thioredoxin domain and three CGFS active-site motif-containing GRX domains that coordinate three iron-sulfur (Fe-S) clusters in a glutathione-dependent manner. As an Fe-S cluster-charged holoenzyme, GRXS17 is likely involved in the maturation of cytosolic and nuclear Fe-S proteins. In addition to its role in cluster biogenesis, GRXS17 presented both foldase and redox-dependent holdase activities. Oxidative stress in combination with heat stress induced loss of its Fe-S clusters followed by subsequent formation of disulfide bonds between conserved active-site cysteines in the corresponding thioredoxin domains. This oxidation led to a shift of GRXS17 to a high-molecular-weight complex and thus activated its holdase activity in vitro. Moreover, GRXS17 was specifically involved in plant tolerance to moderate high temperature and protected root meristematic cells from heat-induced cell death. Finally, GRXS17 interacted with a different set of proteins upon heat stress, possibly protecting them from heat injuries. Therefore, we propose that the Fe-S cluster enzyme GRXS17 is an essential guard that protects proteins against moderate heat stress, likely through a redox-dependent chaperone activity. We reveal the mechanism of an Fe-S cluster-dependent activity shift that converts the holoenzyme GRXS17 into a holdase, thereby preventing damage caused by heat stress.</AbstractText><CopyrightInformation>© 2020 American Society of Plant Biologists. All Rights Reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Martins</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Knuesting</LastName><ForeName>Johannes</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Plant Physiology, FB5, University of Osnabrück, D-49069 Osnabrueck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bariat</LastName><ForeName>Laetitia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dard</LastName><ForeName>Avilien</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Freibert</LastName><ForeName>Sven A</ForeName><Initials>SA</Initials><AffiliationInfo><Affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marchand</LastName><ForeName>Christophe H</ForeName><Initials>CH</Initials><Identifier Source="ORCID">0000-0002-0729-3841</Identifier><AffiliationInfo><Affiliation>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Young</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dung</LastName><ForeName>Nguyen Ho Thuy</ForeName><Initials>NHT</Initials><Identifier Source="ORCID">0000-0001-6644-1229</Identifier><AffiliationInfo><Affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Voth</LastName><ForeName>Wilhelm</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Debures</LastName><ForeName>Anne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saez-Vasquez</LastName><ForeName>Julio</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-2717-7995</Identifier><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Centre National de la Recherche Scientifique, F-66860 Perpignan, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lemaire</LastName><ForeName>Stéphane D</ForeName><Initials>SD</Initials><Identifier Source="ORCID">0000-0001-6442-0547</Identifier><AffiliationInfo><Affiliation>Institut de Biologie Physico-Chimique, Unité Mixte de Recherche 8226, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Unité Mixte de Recherche 7238, Centre National de la Recherche Scientifique, Sorbonne Université, F-75005 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lill</LastName><ForeName>Roland</ForeName><Initials>R</Initials><Identifier Source="ORCID">0000-0002-8345-6518</Identifier><AffiliationInfo><Affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Messens</LastName><ForeName>Joris</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-2128-8264</Identifier><AffiliationInfo><Affiliation>VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brussels Center for Redox Biology, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scheibe</LastName><ForeName>Renate</ForeName><Initials>R</Initials><Identifier Source="ORCID">0000-0002-6140-6181</Identifier><AffiliationInfo><Affiliation>Institut für Zytobiologie und Zytopathologie, Philipps-Universität, Marburg 35032, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reichheld</LastName><ForeName>Jean-Philippe</ForeName><Initials>JP</Initials><Identifier Source="ORCID">0000-0001-6884-0602</Identifier><AffiliationInfo><Affiliation>Laboratoire Génome et Développement des Plantes, Université Perpignan Via Domitia, F-66860 Perpignan, France 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DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Plant Physiol</MedlineTA><NlmUniqueID>0401224</NlmUniqueID><ISSNLinking>0032-0889</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32826321</ArticleId><ArticleId IdType="pii">pp.20.00906</ArticleId><ArticleId IdType="doi">10.1104/pp.20.00906</ArticleId><ArticleId IdType="pmc">PMC7536686</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Plant Physiol. 2016 Oct;172(2):858-873</Citation><ArticleIdList><ArticleId IdType="pubmed">27503603</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant. 2013 Mar;6(2):323-36</Citation><ArticleIdList><ArticleId IdType="pubmed">23024205</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Rep. 2018 Feb 13;22(7):1657-1665</Citation><ArticleIdList><ArticleId IdType="pubmed">29444421</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Chem Biol. 2015 Oct;11(10):772-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26302480</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2007 Jan;9(1):151-7</Citation><ArticleIdList><ArticleId IdType="pubmed">17115894</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13735-40</Citation><ArticleIdList><ArticleId IdType="pubmed">26483494</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2000 Dec 8;275(49):38302-10</Citation><ArticleIdList><ArticleId IdType="pubmed">10976105</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2008 Apr 4;283(14):8868-76</Citation><ArticleIdList><ArticleId IdType="pubmed">18216016</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2016 Jul 14;166(2):369-379</Citation><ArticleIdList><ArticleId IdType="pubmed">27293188</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2009 Jun;150(2):552-61</Citation><ArticleIdList><ArticleId IdType="pubmed">19339505</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2005 Aug 18;436(7053):1035-39</Citation><ArticleIdList><ArticleId IdType="pubmed">16110529</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Bot. 2018 Jun 19;69(14):3491-3505</Citation><ArticleIdList><ArticleId IdType="pubmed">29194485</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2011 Jul 20;475(7356):324-32</Citation><ArticleIdList><ArticleId IdType="pubmed">21776078</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Metab. 2010 Oct 6;12(4):373-385</Citation><ArticleIdList><ArticleId IdType="pubmed">20889129</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Mol Life Sci. 2009 Aug;66(15):2539-57</Citation><ArticleIdList><ArticleId IdType="pubmed">19506802</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2017 Nov 20;27(15):1235-1251</Citation><ArticleIdList><ArticleId IdType="pubmed">28537421</ArticleId></ArticleIdList></Reference><Reference><Citation>Sci Rep. 2017 Nov 21;7(1):15950</Citation><ArticleIdList><ArticleId IdType="pubmed">29162892</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2013 Jul 24;4:259</Citation><ArticleIdList><ArticleId IdType="pubmed">23898337</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 1998 Dec;16(6):735-43</Citation><ArticleIdList><ArticleId IdType="pubmed">10069079</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2007 Jun;19(6):1851-65</Citation><ArticleIdList><ArticleId IdType="pubmed">17586656</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2008 Apr 9;27(7):1122-33</Citation><ArticleIdList><ArticleId IdType="pubmed">18354500</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2004 Sep 17;279(38):39999-40006</Citation><ArticleIdList><ArticleId IdType="pubmed">15258152</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2017 Jun 19;8:1045</Citation><ArticleIdList><ArticleId IdType="pubmed">28674546</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3095-103</Citation><ArticleIdList><ArticleId IdType="pubmed">26038575</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2007 May 1;104(18):7379-84</Citation><ArticleIdList><ArticleId IdType="pubmed">17460036</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2011 Dec 2;286(48):41499-509</Citation><ArticleIdList><ArticleId IdType="pubmed">21931161</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9559-64</Citation><ArticleIdList><ArticleId IdType="pubmed">23671085</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2011 Jun 10;286(23):20398-406</Citation><ArticleIdList><ArticleId IdType="pubmed">21515673</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Biotechnol J. 2012 Oct;10(8):945-55</Citation><ArticleIdList><ArticleId IdType="pubmed">22762155</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2018 May 17;70(4):614-627.e7</Citation><ArticleIdList><ArticleId IdType="pubmed">29754824</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Bot. 2020 Aug 6;71(16):4843-4857</Citation><ArticleIdList><ArticleId IdType="pubmed">32309856</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Bot. 2014 Jun;65(11):2883-93</Citation><ArticleIdList><ArticleId IdType="pubmed">24307718</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2016 Mar;170(3):1284-99</Citation><ArticleIdList><ArticleId IdType="pubmed">26672074</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8168-73</Citation><ArticleIdList><ArticleId IdType="pubmed">15917333</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2012 Oct 15;17(8):1124-60</Citation><ArticleIdList><ArticleId IdType="pubmed">22531002</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2011 Aug 5;286(31):27515-27</Citation><ArticleIdList><ArticleId IdType="pubmed">21632542</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2017 Sep 30;491(4):1034-1039</Citation><ArticleIdList><ArticleId IdType="pubmed">28780355</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2017 Jan 4;45(D1):D1064-D1074</Citation><ArticleIdList><ArticleId IdType="pubmed">27899614</ArticleId></ArticleIdList></Reference><Reference><Citation>J Microsc. 2008 Aug;231(2):299-316</Citation><ArticleIdList><ArticleId IdType="pubmed">18778428</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Sci. 2012 Oct;195:10-23</Citation><ArticleIdList><ArticleId IdType="pubmed">22920995</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Genet. 2019 Apr 29;15(4):e1008094</Citation><ArticleIdList><ArticleId IdType="pubmed">31034471</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2010 Aug 13;39(3):321-31</Citation><ArticleIdList><ArticleId IdType="pubmed">20705236</ArticleId></ArticleIdList></Reference><Reference><Citation>Dev Cell. 2017 Dec 4;43(5):618-629.e5</Citation><ArticleIdList><ArticleId IdType="pubmed">29056551</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 1999 Feb 5;96(3):341-52</Citation><ArticleIdList><ArticleId IdType="pubmed">10025400</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Cell. 2013 Jun;24(12):1895-903</Citation><ArticleIdList><ArticleId IdType="pubmed">23615448</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Chem. 2014 Aug 26;2:70</Citation><ArticleIdList><ArticleId IdType="pubmed">25207270</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2008 Nov 14;135(4):691-701</Citation><ArticleIdList><ArticleId IdType="pubmed">19013278</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Genet. 2009;43:335-67</Citation><ArticleIdList><ArticleId IdType="pubmed">19691428</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Methods. 2008 Jun 23;4:15</Citation><ArticleIdList><ArticleId IdType="pubmed">18573203</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell Environ. 2012 Feb;35(2):360-73</Citation><ArticleIdList><ArticleId IdType="pubmed">21767278</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell Environ. 2017 Oct;40(10):2319-2332</Citation><ArticleIdList><ArticleId IdType="pubmed">28741719</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9565-70</Citation><ArticleIdList><ArticleId IdType="pubmed">23690600</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Struct Mol Biol. 2016 Jan;23(1):53-58</Citation><ArticleIdList><ArticleId IdType="pubmed">26619265</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant. 2014 Jan;7(1):187-205</Citation><ArticleIdList><ArticleId IdType="pubmed">24203231</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Plant Biol. 2008;59:143-66</Citation><ArticleIdList><ArticleId IdType="pubmed">18444899</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2009 Aug 13;460(7257):831-8</Citation><ArticleIdList><ArticleId IdType="pubmed">19675643</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5978-83</Citation><ArticleIdList><ArticleId IdType="pubmed">19293385</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2016 Jun 30;166(1):140-51</Citation><ArticleIdList><ArticleId IdType="pubmed">27264606</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2018 Mar 1;28(7):609-624</Citation><ArticleIdList><ArticleId IdType="pubmed">28594234</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2004 Dec 10;279(50):51923-30</Citation><ArticleIdList><ArticleId IdType="pubmed">15456753</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2015 Jun;1853(6):1513-27</Citation><ArticleIdList><ArticleId IdType="pubmed">25264274</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2019 Jun 04;10:712</Citation><ArticleIdList><ArticleId IdType="pubmed">31231405</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods Enzymol. 2018;599:197-226</Citation><ArticleIdList><ArticleId IdType="pubmed">29746240</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Bot. 2014 Aug;65(15):4159-75</Citation><ArticleIdList><ArticleId IdType="pubmed">24803505</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Commun. 2017 Apr 04;8:14835</Citation><ArticleIdList><ArticleId IdType="pubmed">28374771</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Commun. 2020 Apr 7;11(1):1725</Citation><ArticleIdList><ArticleId IdType="pubmed">32265442</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Genet. 2015 Mar 25;11(3):e1005106</Citation><ArticleIdList><ArticleId IdType="pubmed">25806539</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013 Nov 12;8(11):e78948</Citation><ArticleIdList><ArticleId IdType="pubmed">24265733</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2017 Jun;90(5):856-867</Citation><ArticleIdList><ArticleId IdType="pubmed">27801967</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Struct Biol. 2018 Feb;48:1-5</Citation><ArticleIdList><ArticleId IdType="pubmed">28734135</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2015 Apr;167(4):1643-58</Citation><ArticleIdList><ArticleId IdType="pubmed">25699589</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2008 Feb 14;451(7180):851-4</Citation><ArticleIdList><ArticleId IdType="pubmed">18235446</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2014 Oct 2;56(1):116-27</Citation><ArticleIdList><ArticleId IdType="pubmed">25242142</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Struct Mol Biol. 2007 Sep;14(9):875-7</Citation><ArticleIdList><ArticleId IdType="pubmed">17704817</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2016 Oct 21;291(43):22344-22356</Citation><ArticleIdList><ArticleId 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